Risk warning: Spread bets and CFDs are complex, leveraged products — most retail accounts lose money. Check any provider's published loss rate, and never risk money you can't afford to lose.
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Spread betting vs CFDs

Same engine — leverage, long or short, no ownership of the underlying — different wrapper. For most UK retail traders the deciding factor is tax.

Spread bettingCFD trading
UK taxNo Capital Gains Tax or stamp duty on profits under current rulesCGT applies (18–24% above the £3,000 allowance); losses can offset other gains
AvailabilityUK & Ireland onlyMost countries (banned for US retail)
Pricing£ per point; expiry or daily rollingContracts in the asset's own currency
Loss offsetLosses cannot be offset against taxable gainsLosses can be offset — relevant if you also hold taxable investments
Typically suitsUK tax residents speculating short-termNon-UK residents; hedgers wanting loss relief; professionals

Which should you choose?

If you are a UK tax resident trading speculatively, spread betting's CGT exemption usually wins — especially now the annual CGT allowance is only £3,000. If you are hedging a taxable portfolio, CFD losses can offset gains elsewhere, which spread betting losses cannot. If you are outside the UK and Ireland, the choice is made for you: spread betting isn't available.

Costs are broadly similar at the same provider, and under FCA rules the leverage caps, margin-close-out protections and negative-balance protection apply equally to both. See the tax guide for HMRC's position in detail — and if you're weighing leveraged products against simply buying shares, read spread betting vs share dealing.